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Recently there have been medical research reports indicating that all the warnings about consuming too much salt were exaggerated. Perhaps you remember when we were told that consuming eggs would clog our arteries with cholesterol, and anyone eating butter had a death wish. Now, eggs are an ideal source of lean protein and butter not only isn’t bad, it is superior to margarine. In that vein, having seen the newer reports, I was largely ignoring salt warnings (particularly since I can eat my weight in restaurant chips and salsa). Then this report popped-up. Quoting from the study: “…excess dietary salt suppresses resting cerebral blood flow and endothelial function, leading to cognitive decline.”  Cognitive decline, of course, isn’t good. It causes little brains. Research Details Researchers from Weill Cornell Medical College fed mice a high salt diet. Admittedly, it was a very high salt diet. The result was reduced blood flow to the hippocampus and cortex. Our ol...

We’ve found some simply delicious research reports. Chocolate Lovers- Take Heart! Denmark has created a large health study, with over 55,000 participants who have been tracked for over 13 years. Originally designed to identify cancer risk factors, it captured sufficiently rich and detailed information that it can be used to assess heart health benefits as well. Research teams from Beth Israel Deaconess Hospital in Boston, and Aalborg University Hospital in Aalborg Denmark teamed up. Kim Overvad, PhD in Epidemiology at Aalborg University Hospital took the lead; Murray A. Mittleman, MD of Beth Israel and Elizabeth Mostofsky, ScD and a post-doc at Beth Israel also worked on it. The researchers were trying to determine if consumption of chocolate reduced the risk of atrial fibrillation. Atrial fibrillation is commonly called “afib” here in the U.S. It’s likely you’ve seen advertisements for medications to treat it. Afib is associated with a higher risk of stroke, dementia, heart fai...

We’ve pounded the drum on exercise being the best single thing one can do for brain health. There is much cool new news for both adults and kids on this topic. But first let’s recap: ·          The landmark study on exercise and brain health was done in 2002 by Professor of Neurology at University of California-Irvine Carl Cotman, PhD and Nicole Berchtold, PhD, also of UCI. They found that exercise directly improves brain function. Previously, the assumption was that the benefit was indirect through improved heart function causing better blood circulation in the brain. Research here . ·          Dr. Yorgi Mavros of the University of Sydney and Dr. Nicola Gates of the University of New South Wales research showed that Progressive Resistance Training (PRT) improved brain function and cognition. Research here . ·          Mount Sinai School of Medicine Post...

We’ve noticed a recurring theme in recent brain health scientific studies called “speed of processing”. Adults with faster information processing capability seem less susceptible to various forms of dementia including Alzheimer’s disease.  We’ve previously discussed some of these studies; most were focused on selected groups of individuals such as older adults. Further, those studies typically concentrated on brain parts known to play a critical role in memory formation and fast response, usually the fornix and the hippocampus, parts of the limbic system. Does White Matter Matter?   Researchers at Tohoku University in Sendai Japan have taken a different approach with their analysis. They performed a large study of healthy young adults to understand if the overall amount of white matter in the brain was associated with faster processing speed. White matter is bundles of axons which connect various gray matter areas to each other and to the spinal cord. In our “ Veg...

In our last post, we discussed the research about the cognition benefit from playing Super Mario . New research qualifies the kind of games that might help. Not all will. Kind of Good News About Video Games A large study (2,800+ participants) performed by researchers from Indiana University, South Florida University of South Florida and Penn State University tracked individuals over 10 years. Participant groups received memory, reasoning, or speed of processing training, or were part of a control group. If you’ve had a vision study at your ophthalmologist, you’ve done something like the speed of processing video game used in the study. To play, you must spot something, such as a highway sign on a roadway, and then spot something else in the periphery. The faster you identify and click on the objects, the better you score. As the game proceeds, the background becomes more complex making it harder to find the images. The good news: participants playing that type of game had a ...

This brain builder is so good that we are quoting the title as published in a prestigious scientific journal : “Playing Super Mario 64 increases hippocampal grey matter in older adults.” It seems that some researchers from Montreal and St. John’s Newfoundland have nothing better to do than play video games. Well, not exactly. Gregory L. West, PhD and Benjamin Rich Zendel PhD, put together a research team to see if the brains of older adults would benefit from playing video games and, if so, exactly how. The team from the Faculty of Medicine at Memorial University of Newfoundland and from the Centre de Researche en Neurologie et Cognition at the University of Montreal, recruited 33 adults from ages 55 to 75. They used the standard test method with a control group and subject groups. The control group continued their normal activities. A second group took self-directed piano lessons (as we’ve covered before, research shows notable brain growth from learning to play a musical in...

Get Married; Have a Better Brain Married couples have a significantly lower risk of Alzheimer’s disease than single individuals. We didn’t see that finding coming.  A research paper in the Journal of Neurology, Neurosurgery and Psychiatry reported that singles had a 42% higher risk of dementia than couples. Widowed had an average of 20% higher. Curiously, divorced individuals had the same risk as married. Andrew Sommerlad, MD of the University of London, along with fellow researchers Joshua Ruegger and Archana Singh-Manoux MD, speculate that the benefit comes from social contact, communication, looking-out for each other and more mental activity. (We’ve written before on the extreme detriment of loneliness on health in general and brain health in particular). We’re speculating that the punch line is to get married if you’re not…. Build Up Endurance; Build Better Working Memory We were recently explaining to someone that one of the reasons that biological medicines a...

Middle-age spread associated with Alzheimer’s, and why Google may be bad for your brain. The News About Fat Just Keeps Getting Worse The Journal of Alzheimer’s and Dementia reported the results of a study on fat as an Alzheimer’s factor. This very large study-1.3 million subjects- reviewed data comparing Body Mass Index (BMI) to incurrence of dementia. BMI measures the relationship between height and weight. The finding was stark and severe: being over-weight at middle age increases the risk of dementia later in life . The study was performed by a highly-respected research team, led by Psychology Professor Mika Kivimaki at University College London and Ritva Luukkonen from the Department of Mathematics and Statistics at the University of Helsinki and included experts from throughout Europe. Study details here . Consumer safety tip: it contains math you didn’t see in high school. Is Google Shrinking Your Brain ? Frank Gunn-Moore is a professor at the University of St And...

While you sleep, your glymphatic system shampoos your brain. It gives it a good cleaning and eliminates any toxins or bad stuff that has managed to slip in. Of course, your brain is performing an endless number of other functions as well. But the cleaning function is different in that it only is performed while you sleep. And if you don’t sleep enough, well, you’re trying to do your waking tasks with a clogged-up, messy, dirty brain. It is possible- although speculative at this point- that there may be a link between inadequate sleep and Alzheimer’s disease. Enough’ s Enough How much sleep do you need? We came across a newsletter from the Cleveland Clinic with some information on appropriate amounts of sleep that referenced guidelines from a variety of sources including National Sleep Foundation, American Academy of Pediatrics and the American Academy of Sleep Medicine. Obviously, infants and babies sleep most of the time, furthermore, they need to. Toddlers (ages 1-3) need 12...

When’s the last time you read a novel? When’s the last time you read one and really thought about it? If you answered college, or even high school, you may want to pick up a best seller, and maybe a classic too. Research from Emory University’s Center for Neuropolicy As we follow research on how to not just maintain a healthy brain, but to grow a bigger one, sometimes we find ourselves surprised. This is one of those situations. We found some research on how reading novels may improve our brains, which made us happy because all of us at Big Brain Place love to read. Gregory Berns, MD, PhD led team of researchers at Emory University who studied the effect of reading a novel on the brain. Dr. Berns, as well as other members of the team, are experts in MRI technology. The scientists established baseline MRI observations for the group of test participants. Then the participants read a section of a novel each day. On the following day, they got an MRI. That process continued unti...

She Blinded Me With Science made it to No. 8 on the Billboard Top 100 in 1982. It was written and recorded by Thomas Dolby, whose real name was Thomas Robertson. Robertson had become so skilled with recording equipment and the like that his friends nicknamed him Dolby, for the rather more famous noise reduction and sound reproduction company Dolby Laboratories. Brain Science This post is pretty “sciency”, hence that introduction. Three brain factoids to set the stage: ·          One part of the brain is the hippocampus , which we’ve mentioned in previous blog posts. It is part of the limbic system and plays an essential part in the formation of new memories and is involved in learning. ·          Neuroplasticity is a term that means that the brain can change-or be “plastic” into adulthood. One of the most important things we’ve learned in recent times is that the brain is “plastic” in adulthood...

A good night’s sleep may help you manage fear and risks better. A study just posted in Journal of Neuroscience describes the importance of a good night’s sleep to controlling strong emotions, especially fear. Previous studies in this area attempted to discover what happens in the brain after a frightful experience.  These prior studies, for example, show how Post-Traumatic Stress Disorder (PTSD) affects sleep. A team at the Rutgers University Center for Molecular and Behavioral Neuroscience, led by Itamar Lerner, has taken a different approach. They wanted to see if there is a relationship between adequate sleep and prevention or management of the brain’s reaction to subsequent stressful events. Research Team Lerner is a Postdoctoral Fellow in sleep research. Along with fellow researchers Neha Sinha-also doing Postdoctoral research-in her case in brain imaging, Shira Lupkin and Alan Tsai, they used new technology that allows mobile tracking of sleep habits over a per...

Soda can make you stupid, or worse. Sometimes we find research reports on brain health that are sobering. There was a rather spooky one we just read. But we also discovered one that is positive. Here’s the tough medicine first.   Artificial Sweeteners May Be Bad For You   Here’s the punch line: “Daily diet soda drinkers three times more likely to develop stroke and dementia compared to those who don’t”. You might have seen that headline before. It drew a lot of publicity. Now, remember your statistics class: correlation doesn’t mean causation. Just because the years that skirt hemlines go up are also years that the stock market goes up doesn’t mean short skirts cause the stock prices to increase. It could be that other things diet soda drinkers do – or don’t do- is the reason they are more likely to have a stroke or get dementia.   Here’s  a link to a summary of the research  if you want to read more. The research was done by a team from Boston U...

If you do it right, puzzles and games might just save your brain. There are millions of players of strategy games, memory games, word games and puzzles. They want to know that working crosswords, solving sudoku, playing bridge, mahjong or chess will help preserve mental acuity. Some are counting on it. Cognitive Reserve Cognitive reserve is the term developed after researchers found instances of examination of the brains of individuals that showed signs of dementia or Alzheimer’s disease, but, while alive, the individual had exhibited no signs of dementia.  We want to build cognitive reserve, and there is evidence that puzzles can do that. One key-and positive- study from 2011 found that solving crossword puzzles delayed onset of memory loss by 2.5 years, and may have had much longer beneficial impact. NIH Research The National Institute of Health and the National Institute of Nursing Research funded a study on brain-training and cognition. That study is related-ad...

Your brain has an Executive Function . Executive function is the scientific term for our ability to organize activity, learn from past experiences, make plans, solve problems and work puzzles. Some Science Among the areas in the brain involved in executive function are the medial frontal cortex and the lateral prefrontal cortex . Robert M.G. Reinhart PhD and Assistant Professor of Psychology at Boston University notes that those two areas control most of the executive function. He calls these areas “ the alarm bell of the brain ”. Reinhart is the Director of the Visual Cognitive Neuroscience at Boston University and, among other area of brain research, has been studying ways to employ electrical stimulation to improve performance in learning and self-control. “If you make an error, this brain area fires. If I tell you that you make an error, it also fires. If something surprises you, it fires,” says Reinhart. More Science Kimberly Luu, currently doing graduate s...

Tuesday, the CDC reported that being overweight or obese is associated with higher risk of 13 different cancers. They put it into perspective with two additional pieces of data: first, two-thirds of American adults are overweight , and second, in 2014, there were 630,000 diagnoses of those forms of cancer in the U.S. That is, there were 630,000 cases of the kinds of cancer associated with being overweight. Over a third of Americans are obese. Now, that’s not someone’s judgement call. That is a statistical finding, based on studies of body mass index (BMI). Here's the formula for BMI so that you can calculate it for yourself. You may want to convert your height and weight into meters; some of the formulas I’ve found use the metric system. Here's a converter for inches into meters. A friend of mine said he is writing a three-hundred-page book on diet. On one page it has “Eat Less”. The facing page has “Exercise More”, for all three hundred pages. There is no mystery...